Δρ. Γεώργιος Βαλσαμάκης

ΕΡΕΥΝΗΤΙΚΟ ΣΥΓΓΡΑΦΙΚΟ ΕΡΓΟ

ΔΗΜΟΣΙΕΥΣΕΙΣ ΣΕ ΔΙΕΘΝΗ ΕΠΙΣΤΗΜΟΝΙΚΑ ΠΕΡΙΟΔΙΚΑ: 39,   Impact Factor 200,418 ,citation 1785, h-factor 17)

1. Valsamakis G, Papatheodorou DC, Chalarakis N, Vrachnis N, Sidiropoulou EJ, Manolikaki M, Mantzou A, Margeli A, Papassotiriou I, Chrousos GP, Mastorakos G. In pregnancy increased maternal STAI trait stress score shows decreased insulin sensitivity and increased stress hormones. 2017 Jun 13;84:11-16.
2. Valsamakis G, Konstantakou P, Mastorakos G. New targets for drug treatment of obesity. Annual Review Pharmacol Toxicol Jan 6;57:585-605, 2017
3. Paltoglou G, Schoina M, Valsamakis G, Salakos N, Avloniti A, Chatzinikolaou A, Margeli A, Skevaki C, Papagianni M, Kanaka-Gantenbein C, Papassotiriou I, Chrousos GP, Fatouros IG, Mastorakos G. Interrelations among the adipocytokines leptin and adiponectin, oxidative stress and aseptic inflammation markers in pre- and early-pubertal normal-weight and obese boys. Endocrine. 2017 Mar;55(3):925-933
4. Konstantakou P, Mastorakos G, Vrachnis N, Tomlinson JW, Valsamakis G. Dysregulation of 11beta-Hydroxysteroid Dehydrogenases; Implications during pregnancy and beyond. J Matern Fetal Neonatal Med. 2016 Mar 28:1-28.
5. Valsamakis G, Kyriazi EL, Mouslech Z, Siristatidis C, Mastorakos G . Effect of maternal obesity on pregnancy outcomes and long-term metabolic consequences. Hormones (Athens). 2015 Jul-Sep;14(3):345-57
6. Maryam Nasiri, Nikolaos Nikolaou, 3, Silvia Parajes Nils P Krone, George Valsamakis,George Mastorakos, Beverly Hughes, Angela Taylor, Iwona J Bujalska, Laura L Gathercole, Jeremy W Tomlinson. 5α-reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes. Endocrinology (London) 2015 Aug;156(8):2863-71
7. Paltoglou George, Fatouros Ioannis, Valsamakis George, Schoina Maria, Papagianni Maria, Mantzou Aimilia, Kanaka-Gantenbein Christina, Chrousos George P., Mastorakos George. “Antioxidation improves in puberty in normal weight and obese boys, in positive association with exercise-stimulated growth hormone secretion.” Pediatric Research 2015 Aug;78(2):158-64
8. Lois K, Karavis M, Mastorakos G, Valsamakis G New molecular targets for the Pharmacotherapy of Obesity.

In: De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.2015 Apr

9. Georgios Valsamakis, Dimitrios Papatheodorou, Evangelia Kyriazi, Aikaterini Naoum, Alexandra Margeli, Ioannis Papassotiriou, Efthymios Kapantais, Ioannis G. Papassotiriou, Sudhesh Kumar and George Mastorakos. Neonatal birth waist is positively predicted by second trimester maternal active ghrelin, a pro-appetite hormone, and negatively associated to third trimester maternal leptin, a pro-satiety hormone. Early Human Development 2014 Sep;90(9):487-92.
10. G Valsamakis, K Lois, S Kumar , G Mastorakos. New molecular targets in the pathophysiology of obesity and available treatment options under investigation. Clinical Obesity (Wiley, London) August 2014 2014 Aug;4(4):209-19
11. Vrachnis N, Zygouris D, Iliodromiti Z, Daniilidis A, Valsamakis G, Kalantaridou S Probing the impact of sex steroids and menopause-related sex steroid deprivation on modulation of immune senescence. Maturitas. 2014 Jul;78(3):174-8
12. Vrachnis N, Vlachadis N, Iliodromiti Z, Valsamakis G, Creatsas G Austerity and health in Greece. 2014 May 3;383(9928):1543-4
13. G Valsamakis, D C Papatheodorou, A Margeli, V Bakoulas, E Kapantais, I Papassotiriou, G Creatsas, S Kumar, G Mastorakos. First trimester maternal BMI is a positive predictor of cord blood c-peptide levels while maternal visfatin levels are negative predictors of birth weight. Hormones 2014, 13(1):87-94
14. D C. Papatheodorou, L Karagiannidis, A Margeli, G Paltoglou, G Kaparos G, G Valsamakis, G. Chroussos, G Creatsas, G Mastorakos. Pulsatile interleukin-6 leads CRH secretion and is associated with myometrial contractility during the active phase of term human labor. Journal of Clin Endo Metab 2013 Oct;98(10):4105-4112
15. Valsamakis G, Lois K, Mastorakos G, Kumar S. Metabolic and other effects of pioglitazone as an add-on therapy to metformin in the treatment of polycystic ovary syndrome (PCOS). Hormones 2013 12 (3):363-378
16. Markopoulos MC,Valsamakis G, Kouskouni E, Boutsiadis A, Papassotiriou I, Creatsas G, Mastorakos G Study of carbohydrate metabolism indices and adipocytokine profile and their relationship to androgens in polycystic ovary syndrome after menopause. Eur J Endocrinol. 2012 Oct  168(1):83-90
17. Markopoulos M, Rizos D, Valsamakis G, Grigoriou O, Chroussos G, Creatsas G, Mastorakos G. Hyperandrogenism in women with polycystic ovary syndrome persists after menopause. J Clin Endo Metab 2011:96:623-631
18. K Lois, G Valsamakis, G Mastorakos, S Kumar. The impact of insulin resistance in womans health and potential treatment options. Ann N Y Acad Sci Sep;1205:156-65, 2010
19. Vitoratos N, Vrachnis N, Valsamakis G, Panoulis K, Creatsas G. Perinatal mortality in diabetic pregnancy. Ann N Y Acad Sci. 2010 Sep;1205:94-8
20. G Valsamakis, S Kumar, G Creatsas, G Mastorakos. The effects of adipose tissue and adipocytokines in human pregnancy. Ann N Y Acad Sci Sep;1205:76-81, 2010

21. Valsamakis, A. Margeli, N. Vitoratos, A.Boutsiadis, E.G. Sakkas, G. Papadimitriou, N. M. Al-Daghri, D.Botsis, S. Kumar, I. Papassotiriou, G. Creatsas, G. Mastorakos. The role of maternal gut hormones in normal pregnancy: Fasting plasma active GLP-1 level is a negative predictor of fetal abdomen circumference and maternal weight change. Eur J Endocrinol 2010 162 897–903
22. G. Mastorakos, Valsamakis, G. Paltoglou, G. Creatsas. Management of obesity in menopause: Diet, exercise, pharmacotherapy and bariatric surgery. Maturitas 2010, Mar;65(3):219-24
23. Bawazeer NM, Al-Daghri NM, Valsamakis G, Al-Rubeaan KA, Sabico SL, Huang TT, Mastorakos GP, Kumar S. Sleep duration and quality associated with obesity among Arab children Obesity (Silver Spring). 2009 Dec;17(12):2251-3.
24. Vitoratos N, Valsamakis G, Mastorakos G, Boutsiadis A, Salakos N, Kouskouni E, Creatsas G. Pre- and early post-partum adiponectin and interleukin-1beta levels in women with and without gestational diabetes. Hormones (Athens). 2008 Jul-Sep;7(3):230-6
25. Dixon AN, Valsamakis G, Hanif W, Field A, Boutsiadis A, Harte A, McTernan PG, Barnett AH, Kumar S. Effect of the orlistat on serum endotoxin lipopolysaccharide and adipocytokines in South Asian individuals with impaired glucose tolerance. Int J Clin Pract. 2008 Jul;62(7):1124-9
26. Valsamakis G, Jones A, Chetty R, McTernan PG, Boutsiadis A, Barnett AH, Banerjee AK, Kumar S. MRI total sagittal abdominal diameter as a predictor of metabolic syndrome compared to visceral fat at L4-L5 level. Curr Med Res Opin. 2008 Jul;24(7):1853-60
27. WM Hanif, G Valsamakis, A. Dixon, A F Jones, A H Barnett, S Kumar. Detection of impaired glucose tolerance and undiagnosed type 2 diabetes in British Indo-Asians: an effective screening strategy. Diabetes Obesity and Metabolism, 2008, 10; 755-82
28. Mastorakos G, Valsamakis G, Papatheodorou DC, Barlas I, Margeli A, Boutsiadis A, Kouskouni E, Vitoratos N, Papadimitriou A, Papassotiriou I, Creatsas G.The role of adipocytokines in insulin resistance in normal pregnancy: visfatin concentrations in early pregnancy predict insulin sensitivity. Clin Chem. 2007 Aug;53(8):1477-83.
29. G Mastorakos, Valsamakis G, Kanaka-Gantenbein C, Malamitsi-Puchner, Mastorakos G. Causes of intrauterine growth restriction and the postnatal development of the metabolic syndrome. Ann N Y Acad Sci 2006, Dec 2006, Vol 1092: 138-147
30. Kyrou I, Valsamakis G, Tsigos C. Endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome. Ann N Y Acad Sci, Nov 2006, Volume 1083 : 270-305
31. Valsamakis G, Chetty R, Anwar AJ, Banerjee AK, Barnett AH, Kumar S. Association of simple anthropometric measures of obesity with MRI-assessed visceral fat and the metabolic syndrome in male Caucasian and Indo-Asian patients. Diabetic Medicine 2004; 21(12):1339-1345

32. Valsamakis G, Anwar A, Shackleton CHL, McTernan PG, Chetty R, Tomlinson J, Wood P, Banerjee AK, Holder G, Barnett AH, Stewart P, Kumar S. 11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus. J Clin Endocrinol Metab 2004, 89 (9):4755-61

33. Valsamakis G, McTernan PG, Chetty R, Al Daghri N, Field A, Hanif W, Barnett AH, Kumar S. Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines.

34. Ticca V, Hanif W, Anderssen A, G Valsamakis, Barnett AH, Kumar S, Sanjeevi CB. Frequency of Latent Autoimmune Diabetes in Adults in Asian Patients Diagnosed as Type 2 Diabetes in Birmingham, UK. Ann N Y Acad Sci ‘Immunology of Diabetes II: pathogenesis from mouse to man’, 2003; 1005: 356-59.
35. Mc Ternan PG, Fisher ff M, Valsamakis G, Chetty R, Harte AL, Smith SA, Barnett AH, Kumar S. Resistin and type 2 diabetes: Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes. J Clin Endocrinol Metab 2003 Dec 1;88 (12): 6098-6106
36. Fisher ff M, Mc Ternan PG, Valsamakis G, Chetty R, Harte AL, Anwar AJ, Starcynski J, Crocker J, Barnett AJ, Mc Ternan CL, Kumar S. Differences in adiponectin protein expression: Effect of fat depots and type 2 diabetic status. Horm Metab Res 2002;34:650-654
37. Valsamakis G, Chetty R, McTernan PG, Al-Daghri NM, Barnett AH, Kumar S. Fasting serum adiponectin concentration is reduced in Indo-Asian subjects and is related to HDL cholesterol. Diabetes Obes Metab. 2003 Mar;5(2):131-5
38. Valsamakis G, Chetty R, Kumar S. The management of obesity in type 2 diabetes mellitus. Curr Med Res and Opinion 2002; 18 (1): s75-81
39. Valsamakis G, Kumar S. Insulin action enhancers for the management of type 2 diabetes mellitus. Exp Opin Pharmacother 2000;1: 1-9

Further publications (non ISI)

Valsamakis G, Kumar S (Anonymous). Is sibutramine more than a slim hope? Drug and Ther Bulletin; 39 (12):89-92

Valsamakis G, Kumar S. Pharmacological treatment of obesity in patients with diabetes. Modern Diabetes Management 2002;3 (3): 9-12

Valsamakis G Lasaridis P.“Gastroduodenal ulcer: surgical or pharmaceutical intervention? ”Medizinische Welt” Eds FK Schattauer Verlag Stuttgart 1995: 46: 387 – 390,  Germany

Publications submitted: 2

Publications under preparation: 5